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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETS1
All Species:
24.24
Human Site:
Y149
Identified Species:
44.44
UniProt:
P14921
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14921
NP_005229.1
441
50408
Y149
V
N
G
V
N
P
A
Y
P
E
S
R
Y
T
S
Chimpanzee
Pan troglodytes
XP_001170891
731
79148
Q439
N
Q
E
K
T
E
D
Q
Y
E
E
N
S
H
L
Rhesus Macaque
Macaca mulatta
XP_001113198
441
50116
F149
L
S
N
P
G
P
P
F
P
X
X
X
X
X
S
Dog
Lupus familis
XP_546405
441
50378
Y149
V
N
G
V
N
P
T
Y
P
E
S
R
Y
T
S
Cat
Felis silvestris
Mouse
Mus musculus
P27577
440
50183
Y149
V
N
G
A
N
P
T
Y
P
E
S
C
Y
T
S
Rat
Rattus norvegicus
P41156
441
50404
Y149
V
N
G
V
N
P
T
Y
P
E
S
R
Y
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508979
473
53725
Y181
Q
E
K
T
Q
D
Q
Y
L
E
N
S
H
L
T
Chicken
Gallus gallus
P13474
441
50308
Y149
A
N
G
V
N
A
A
Y
P
E
S
R
Y
T
S
Frog
Xenopus laevis
P18755
438
50249
Y146
T
S
E
I
T
P
A
Y
P
E
S
R
Y
T
S
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
T149
S
K
S
S
C
P
A
T
P
M
S
P
M
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51022
623
66848
S155
L
S
G
G
S
T
G
S
T
T
T
T
S
S
G
Honey Bee
Apis mellifera
XP_396368
484
53763
M190
Q
A
A
T
E
S
Y
M
T
P
A
N
Y
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999698
559
62034
E204
H
I
D
M
L
R
K
E
C
D
P
A
N
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
95.9
99
N.A.
97
98.8
N.A.
52.2
95.9
88.6
23.4
N.A.
28.4
32
N.A.
38.1
Protein Similarity:
100
43.2
96.8
99.5
N.A.
98.4
99.3
N.A.
66.5
97.7
93.8
37.6
N.A.
41
42.5
N.A.
50.8
P-Site Identity:
100
6.6
20
93.3
N.A.
80
93.3
N.A.
13.3
86.6
66.6
26.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
6.6
40
93.3
N.A.
80
93.3
N.A.
33.3
86.6
80
26.6
N.A.
40
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
8
31
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
8
8
0
0
8
0
0
0
0
0
% D
% Glu:
0
8
16
0
8
8
0
8
0
62
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
47
8
8
0
8
0
0
0
0
0
0
0
16
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
8
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
0
0
8
0
0
0
8
0
0
0
0
8
8
% L
% Met:
0
0
0
8
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
8
39
8
0
39
0
0
0
0
0
8
16
8
0
0
% N
% Pro:
0
0
0
8
0
54
8
0
62
8
8
8
0
0
8
% P
% Gln:
16
8
0
0
8
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
39
0
0
0
% R
% Ser:
8
24
8
8
8
8
0
8
0
0
54
8
16
16
54
% S
% Thr:
8
0
0
16
16
8
24
8
16
8
8
8
0
47
8
% T
% Val:
31
0
0
31
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
8
0
0
0
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _